Score calculation and percent risk of conversion to secondary-progressive multiple sclerosis over five years. Intended for use in relapsing-remitting multiple sclerosis patients.
To calculate the DAAE Score, determine the points scored for each factor in Table (A). The total sum of these points is the DAAE Score. Reference the DAAE Score with risk group and percent risk of conversion in Table (B).
BACKGROUND INFORMATION
Risk estimates are based on combined data from the United States (Jacobs Multiple Sclerosis Center, n=1,309) and the Netherlands (Multiple Sclerosis Center Amsterdam, n=877). These estimates were generated using data from people with relapsing-remitting multiple sclerosis who were mostly female receiving low-efficacy disease modifying therapy. Risk is reported as a percent with 95% confidence intervals (CI)
The DAAE Score is named from the factors included in the predictive model: Disease duration, Age at disease onset, Age, Expanded Disability Status Scale
Tom A.N. Fuchs 